SalusBioma
Future and gut health
SalusBioma is a useful tool for determining the state of intestinal health, thanks to the quantitative and functional analysis of the resident bacterial and fungal communities.
The Intestinal Microbiome
What it is and why it is so important to analyze it
We are never truly alone. Each of us hosts a thriving population of microorganisms organized in communities and located everywhere in our body: skin, mouth, intestine... We are a “superorganism” composed of human and non-human cells human. Surprisingly, bacterial cells are 10 times more than ours: 100 trillion versus 10 trillion! And most of it is found in the intestine. Bacterial genes make up over 99% of the total! The human microbiome is this: the set of microbes found in our body and their genes< /16>.
Most bacteria do not cause diseases, on the contrary! Scientific studies over the last decade have begun to explain to us how and why the bacteria that live in symbiosis with us are essential for our well-being: microbes digest food to generate nutrients for our cells, synthesize vitamins, metabolize drugs and detoxify carcinogenic molecules, stimulate cell renewal in the intestine and activate and support the immune system.
The microbiome changes depending on the diet, physical activity, the medicines taken and more and more studies correlate the biodiversity of the microbiome to pathological states such as obesity, cardiovascular pathologies, autoimmune diseases, depression, etc., the so-called "diseases of progress" which increasingly afflict rich countries.
The SalusBioma Reports
Different packages for increasingly in-depth analyses
Comparison Table
An easy way to figure out which report is best for your needs
Price | 109€ | 149€ | 199€ |
Biodiversity indices |  | | |
Dysbiosis index | | | |
Phyla analysis | | |  |
Family analysis | | | |
Potentially pathogenic bacteria | | | |
Beneficial bacteria | | | |
Estimation of metabolic activity | | | |
Estimation of fermentation activity | | | |
Estimated vitamin synthesis | | | |
Estimate systemic effects | | | |
Microbiological comment | | | |
Fungal composition | | ||
Indices of fungal dysbiosis | | ||
Potentially pathogenic fungi | | ||
Mycobiological comment | | ||
Total DNA in the sample | | ||
Harmful & beneficial microorganisms | | ||
Metabolic & enzymatic activities | | ||
Inflammation | | ||
Gut-brain axis | | ||
Presence of protozoa | |
Why choose SalusBioma
SalusBioma is synonymous with quality
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Here are some reasons that lead SalusBioma to be a quality analysis:
Technology at the Service of Microbiology
Automation and advanced instrumentation for innovative microbiological analyses
SalusBioma analyzes all the bacteria, and in the Myco version also the fungi, present in the fecal sample, using the metabarcoding technology. The resulting PCR products are read by next generation sequencers (NGS) such as the Illumina MiSeq i100 Plus and analyzed using constantly updated bioinformatics software.
The SalusBioma Total analysis expands the potential through shotgun metagenomics, sequencing entire fecal DNA with NGS and generating millions of high-quality reads. The process allows for taxonomic identification in different kingdoms (Bacteria, Archaebacteria, Fungi, Animals) and functional analysis of the metabolic genes of the microbial community.
The data production process (from acceptance of the sample in the laboratory to the production of the report) is largely automated and each operation is recorded in the internal systems, thus minimizing the possibilities of error and guaranteeing a high quality of the analysis.
Investigation methodology
In order to analyze the intestinal microbiome, a particular analysis is necessary, the 'Next generation sequencing of the 16S rRNA gene'. This test analyzes a bacterial gene called 16S rRNA - a sort of identity card for microbes - and provides the name of all the bacteria present in the sample and their abundance as a result.
Precisely, we extract DNA from feces, amplify the V3-V4 regions of the 16S rRNA gene, sequence them with the Illumina Miseq platform and analyze them with a bioinformatic software called Qiime2, identifying the bacteria against the Greengenes database.
The comparison of each participant's microbiota against the Microbioma Italiano database provides an overview of how one's microbiome influences the health status of the entire organism.
For a more complete and in-depth analysis, the bacterial profile can be analyze with shotgun metagenomics (used in the SalusBioma Total analysis), which is not limite to a single gene region but sequences the entire fecal DNA.